Methanol → 2,2,2-trifluoro-N-(piperidin-4-yl)acetamide

HRID 801921Notes

Reaction equation

HRID 801921 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH2:10][CH:11]([NH:14][C:15]([C:16]([F:17])([F:18])[F:19])=[O:20])[CH2:12][CH2:13]1.[CH3:21][OH:22]>>[NH:8]1[CH2:9][CH2:10][CH:11]([NH:14][C:15]([C:16]([F:17])([F:18])[F:19])=[O:20])[CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 887MethanolHCID 1531300N-(1-benzylpiperidin-4-yl)-2,2,2-trifluoroacetamide

Product 1

HCID 107742532,2,2-trifluoro-N-(piperidin-4-yl)acetamide

Sources & evidence

ORD record
ord-e14c3cddac78404c9fae2188c2f088d7
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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