Imidazole → 1-[Bis(methylphenyl)methyl]imidazole

HRID 80324

Reaction equation

HRID 80324 reaction equation
[C:1]1([C:7]2[CH:12]=[CH:11]N=C(CN3C=CN=C3)[C:8]=2[C:19]2[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=2)[CH:6]=[CH:5][CH:4]=CC=1.[CH3:25]C1C=CC(C(C2C=CC(C)=CC=2)O)=CC=1.S(Cl)(Cl)=O.[NH:45]1[CH:49]=[CH:48][N:47]=[CH:46]1>>[CH3:25][C:24]1[CH:23]=[CH:22][CH:21]=[CH:20][C:19]=1[CH:8]([C:7]1[CH:1]=[CH:6][CH:5]=[CH:4][C:12]=1[CH3:11])[N:45]1[CH:49]=[CH:48][N:47]=[CH:46]1

Participants

5

Reactant 4

HCID 795ImidazoleHCID 24386Thionyl ChlorideHCID 2793564,4'-DimethylbenzhydrolHCID 67427375HCID 67427375, compound

Product 1

HCID 674273871-[Bis(methylphenyl)methyl]imidazole

Procedure

With the same method as for Compound 40, Compound 14 described above, thionyl chloride (Wako Pure Chemical Industries, Ltd.), and imidazole (Wako Pure Chemical Industries, Ltd.) were used, to thereby obtain the title compound.

Sources & evidence

ORD record
ord-90d59c0a8fc3457cb4cc696377965feb
Source dataset
uspto-grants-2014_09
Patent number
US08846012B2

Linked notes

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