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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 80457Generated: October 27, 2026

Tolylboronic acid → 4-[5-(4-Methylphenyl)-1,3-thiazol-2-yl]-1,4-diazatricyclo[4.3.1.13,8]undecane

https://huagongshe.com/reaction/80457

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolylboronic acidHCID 79799—
Reactant4-(5-Bromo-1,3-thiazol-2-yl)-1,4-diazatricyclo[4.3.1.13,8]undecaneHCID 86649262—
Product4-[5-(4-Methylphenyl)-1,3-thiazol-2-yl]-1,4-diazatricyclo[4.3.1.13,8]undecaneHCID 86649263—

Reaction Steps

The title compound was prepared from the product of Example 105A and 4-methylphenylboronic acid according to General Method C: LC-MS Method D (ESI+) m/z 326.0 (M+H)+, retention time 1.54 minutes.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846661B2
Source datasetuspto-grants-2014_09
ORD IDord-ea4f8710fcd445aaa0035d392d882edf
Source noteuspto-grants-2014_09