HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → ethyl 1-(3-fluorophenyl)-3,5-dimethyl-1H-pyrazole-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Ethyl 2-acetylacetoacetate | HCID 79063 | — |
| Reactant | 3-Fluorophenylhydrazine hydrochloride | HCID 2723914 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | ethyl 1-(3-fluorophenyl)-3,5-dimethyl-1H-pyrazole-4-carboxylate | HCID 9856538 | — |
Reaction Steps
Similar to Example 1, equimolar amounts of 3-fluorophenylhydrazine hydrochloride and 2-acetyl-3-oxo-butyric acid ethyl ester were combined in a solution of 50% pyridine in ethanol. Analysis showed that resulting solid was the named product (m.p. 55° C.–56.1° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07087634B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-50a50e2c29a64a198360ea13b9febfaf |
| Source note | uspto-grants-2006_08 |