HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → 1-(3-methoxyphenyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Ethyl 2-acetylacetoacetate | HCID 79063 | — |
| Reactant | 3-Methoxyphenylhydrazine hydrochloride | HCID 2723940 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-(3-methoxyphenyl)-3,5-dimethyl-1H-pyrazole-4-carboxylic acid ethyl ester | HCID 9878654 | — |
Reaction Steps
Similar to Example 1, equimolar amounts of 3-methoxyphenylhydrazine hydrochloride and 2-acetyl-3-oxo-butyric acid ethyl ester were combined in a solution of 50% pyridine in ethanol. The resulting solid was determined to be the named product by 1H-NMR (CDCl3, ppm): 1.38 t (3H); 2.50 s (3H); 2.52 s (3H); 3.84 s (3H); 4.32 q (2H); 6.96 m (3H); 7.3 st (1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07087634B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-6d47505205454e4dbf465abd74ce19e3 |
| Source note | uspto-grants-2006_08 |