HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → ethyl 3-methyl-1-(2-pyridyl)-1H-pyrazole-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 2-Hydrazinopyridine | HCID 78645 | — |
| Reactant | Ethyl 2-formyl-3-oxobutanoate | HCID 14817199 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | ethyl 3-methyl-1-(2-pyridyl)-1H-pyrazole-4-carboxylate | HCID 9877977 | — |
Reaction Steps
Similar to Example 1, equimolar amounts of 2-pyridylhydrazine and 2-formyl-3-oxo-butyric acid ethyl ester were combined in a solution of 50% pyridine in ethanol. Analysis showed that the resulting solid was determined to be the named product (m.p. 49° C.–50° C.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07087634B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-d784be3dc1194f6b9ccfbea658a1aa5c |
| Source note | uspto-grants-2006_08 |