5-Chloro-2-propyl-[1,8]naphthyridine → 4-[4-(3-Bromo-benzyloxy)-2-(7-propyl-[1,8]naphthyridin-4-ylamino)-phenylsulfanyl]-phenol
Reaction equation
[Cl:1][c:2]1[c:3]2[cH:4][cH:5][c:6]([CH2:12][CH2:13][CH3:14])[n:7][c:8]2[n:9][cH:10][cH:11]1.[NH2:15][c:16]1[c:17]([S:31][c:32]2[cH:33][cH:34][c:35]([OH:38])[cH:36][cH:37]2)[cH:18][cH:19][c:20]([O:22][CH2:23][c:24]2[cH:25][c:26]([Br:30])[cH:27][cH:28][cH:29]2)[cH:21]1>>[c:2]1([NH:15][c:16]2[c:17]([S:31][c:32]3[cH:33][cH:34][c:35]([OH:38])[cH:36][cH:37]3)[cH:18][cH:19][c:20]([O:22][CH2:23][c:24]3[cH:25][c:26]([Br:30])[cH:27][cH:28][cH:29]3)[cH:21]2)[c:3]2[cH:4][cH:5][c:6]([CH2:12][CH2:13][CH3:14])[n:7][c:8]2[n:9][cH:10][cH:11]1Participants
3
Sources & evidence
- ORD record
- ord-ea084c4b0f834cf7937c4a6049b86ace
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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