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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 80880Generated: October 26, 2026

1-[3-(Dimethylamino)propyl]piperazine → Dimethyl-(3-{4-[6-(4-trifluoromethylphenyl)pyridazin-3-yl]piperazin-1-yl}propyl)amine, dihydrochloride

https://huagongshe.com/reaction/80880

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[3-(Dimethylamino)propyl]piperazineHCID 2736234—
ReactantPyridazine, 3-chloro-6-[4-(trifluoromethyl)phenyl]-HCID 12449554—
ProductDimethyl-(3-{4-[6-(4-trifluoromethylphenyl)pyridazin-3-yl]piperazin-1-yl}propyl)amine, dihydrochlorideHCID 131730765—

Reaction Steps

The title compound was prepared by a similar procedure to that described in Example 1, starting from 3-chloro-6-(4-trifluoromethylphenyl)pyridazine and (3-dimethylaminoprop-1-yl)piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846677B2
Source datasetuspto-grants-2014_09
ORD IDord-bff784a44e7047a5b87411598c00cd60
Source noteuspto-grants-2014_09