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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 80883Generated: October 26, 2026

1-((1-Methyl-4-piperidinyl)methyl)piperazine → 4-{6-[4-(1-Methylpiperidin-4-ylmethyl)piperazin-1-yl]pyridazin-3-yl}benzonitrile, hydrochloride

https://huagongshe.com/reaction/80883

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-((1-Methyl-4-piperidinyl)methyl)piperazineHCID 2736942—
Reactant3-Chloro-6-(4-cyanophenyl)pyridazineHCID 6405256—
Product4-{6-[4-(1-Methylpiperidin-4-ylmethyl)piperazin-1-yl]pyridazin-3-yl}benzonitrile, hydrochlorideHCID 68490780—

Reaction Steps

The title compound was prepared by a similar procedure to that described in Example 1, starting from 3-chloro-6-(4-cyanophenyl)pyridazine and (1-methylpiperidin-4-ylmethyl)piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846677B2
Source datasetuspto-grants-2014_09
ORD IDord-9b420e15bedd4a7486fcc4dea77ea4ab
Source noteuspto-grants-2014_09