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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 80884Generated: October 27, 2026

1-[(1-Methylpiperidin-3-yl)methyl]piperazine → 4-{6-[4-(1-Methylpiperidin-3-ylmethyl)piperazin-1-yl]pyridazin-3-yl}benzonitrile, trihydrochloride

https://huagongshe.com/reaction/80884

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-[(1-Methylpiperidin-3-yl)methyl]piperazineHCID 2736940—
Reactant3-Chloro-6-(4-cyanophenyl)pyridazineHCID 6405256—
Product4-{6-[4-(1-Methylpiperidin-3-ylmethyl)piperazin-1-yl]pyridazin-3-yl}benzonitrile, trihydrochlorideHCID 131730767—

Reaction Steps

The title compound was prepared by a similar procedure to that described in Example 1, starting from 3-chloro-6-(4-cyanophenyl)pyridazine and (1-methylpiperidin-3-ylmethyl)piperazine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846677B2
Source datasetuspto-grants-2014_09
ORD IDord-c11cc11fed5e42eabcaeb2e45826f10a
Source noteuspto-grants-2014_09