Methanol → 5-Bromo-6-fluoropyridin-3-amine

HRID 809009Notes

Reaction equation

HRID 809009 reaction equation
[Br:1][c:2]1[c:3]([F:11])[n:4][cH:5][c:6]([N+:8]([O-:9])=[O:10])[cH:7]1.[CH3:17][OH:18].[OH2:12].[OH2:13].[Sn:14]([Cl:15])[Cl:16]>>[Br:1][c:2]1[c:3]([F:11])[n:4][cH:5][c:6]([NH2:8])[cH:7]1

Participants

5

Reactant 4

HCID 887MethanolHCID 962Water2×HCID 24479Stannous ChlorideHCID 3451243-Bromo-2-fluoro-5-nitropyridine

Product 1

HCID 183797255-Bromo-6-fluoropyridin-3-amine

Sources & evidence

ORD record
ord-91f20a05104f46709baca30c14ab9ae2
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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