HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Piperidinecarboxamide → 1-(4-{3-[6-(4-Isopropylpiperazin-1-yl)pyridin-3-yl][1,2,4]oxadiazol-5-yl}benzyl)piperidine-4-carboxylic acid amide, dihydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Piperidinecarboxamide | HCID 3772 | — |
| Reactant | 1-(5-(5-(4-Chloromethylphenyl)[1,2,4]oxadiazol-3-yl)pyridine-2-yl)-4-isopropylpiperazine | HCID 15951386 | — |
| Product | 1-(4-{3-[6-(4-Isopropylpiperazin-1-yl)pyridin-3-yl][1,2,4]oxadiazol-5-yl}benzyl)piperidine-4-carboxylic acid amide, dihydrochloride | HCID 131730774 | — |
Reaction Steps
The title compound was prepared by a similar procedure to that described in Example 44, starting from 1-(5-(5-(4-chloromethylphenyl)[1,2,4]oxadiazol-3-yl)pyridine-2-yl)-4-isopropylpiperazine and isonipecotamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08846677B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-2a0917b1d8fb48c4b6287bcee683bb9b |
| Source note | uspto-grants-2014_09 |