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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 80908Generated: October 24, 2026

Diethylaminoethyl chloride → Diethyl-(2-{4-[5-(4-trifluoromethylphenyl)pyridin-2-yl]piperazin-1-yl}ethyl)amine

https://huagongshe.com/en/reaction/80908

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiethylaminoethyl chlorideHCID 13364—
Reactant4-(5-(4-Trifluoromethylphenyl)pyridin-2-yl)piperazineHCID 67145002—
ProductDiethyl-(2-{4-[5-(4-trifluoromethylphenyl)pyridin-2-yl]piperazin-1-yl}ethyl)amineHCID 15951454—

Reaction Steps

The title compound was prepared by a similar procedure to that described in Example 55, starting from 4-(5-(4-trifluoromethylphenyl)pyridin-2-yl)piperazine and 2-diethylaminoethylchloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846677B2
Source datasetuspto-grants-2014_09
ORD IDord-b83450abfbed40da8dad997e3283dbb8
Source noteuspto-grants-2014_09