Potassium Cation → (3-Fluoro-benzyl)-[2-(3-thieno[2,3-d]isoxazol-3-yl-phenoxy)-ethyl]-amine

HRID 809618

Reaction equation

HRID 809618 reaction equation
[Br:1][CH2:2][CH2:3][O:4][c:5]1[cH:6][c:7](-[c:11]2[n:12][o:13][c:14]3[c:15]2[s:16][cH:17][cH:18]3)[cH:8][cH:9][cH:10]1.[C:19](=[O:20])([O-:21])[O-:22].[CH3:34][C:35]#[N:36].[F:25][c:26]1[cH:27][c:28]([CH2:29][NH2:30])[cH:31][cH:32][cH:33]1.[K+:23].[K+:24]>>[CH2:2]([CH2:3][O:4][c:5]1[cH:6][c:7](-[c:11]2[n:12][o:13][c:14]3[c:15]2[s:16][cH:17][cH:18]3)[cH:8][cH:9][cH:10]1)[NH:30][CH2:29][c:28]1[cH:27][c:26]([F:25])[cH:33][cH:32][cH:31]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6342AcetonitrileHCID 19660Carbonate IonHCID 668533-FluorobenzylamineHCID 219835823-[3-(2-Bromo-ethoxy)-phenyl]-thieno[2,3-d]isoxazole

Product 1

HCID 9907296(3-Fluoro-benzyl)-[2-(3-thieno[2,3-d]isoxazol-3-yl-phenoxy)-ethyl]-amine

Sources & evidence

ORD record
ord-e5f2baaa223e44d89b91d88abf979a53
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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