Pyridine → Piperidine-1-sulfonic acid [5-(2,4-dichloro-phenyl)-pyridin-2-yl]-amide

Reaction equation

[Cl:1][c:2]1[c:3](-[c:9]2[cH:10][cH:11][c:12]([NH2:15])[n:13][cH:14]2)[cH:4][cH:5][c:6]([Cl:8])[cH:7]1.[N:16]1([S:22](=[O:23])(=[O:24])[Cl:25])[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21]1.[cH:26]1[cH:27][cH:28][n:29][cH:30][cH:31]1>>[Cl:1][c:2]1[c:3](-[c:9]2[cH:10][cH:11][c:12]([NH:15][S:22]([N:16]3[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21]3)(=[O:23])=[O:24])[n:13][cH:14]2)[cH:4][cH:5][c:6]([Cl:8])[cH:7]1

Participants

Reactant 3

HCID 1049Pyridine

HCID 11298344Piperidine-1-sulfonyl chloride

HCID 624923945-(2,4-Dichlorophenyl)pyridin-2-amine

Product 1

HCID 11717987Piperidine-1-sulfonic acid [5-(2,4-dichloro-phenyl)-pyridin-2-yl]-amide

Sources & evidence

ORD record: ord-948d6917c33d49f5be7bcfaeae3ba62b
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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