Dichloromethane → 1-[2-(4-Bromomethyl-phenyl)-ethyl]-4-phenethyl-1H-pyridin-2-one

Reaction equation

[Cl:30][CH2:31][Cl:32].[OH:1][CH2:2][c:3]1[cH:4][cH:5][c:6]([CH2:9][CH2:10][n:11]2[c:12](=[O:25])[cH:13][c:14]([CH2:17][CH2:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[cH:15][cH:16]2)[cH:7][cH:8]1.[P:26]([Br:27])([Br:28])[Br:29]>>[CH2:2]([c:3]1[cH:4][cH:5][c:6]([CH2:9][CH2:10][n:11]2[c:12](=[O:25])[cH:13][c:14]([CH2:17][CH2:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[cH:15][cH:16]2)[cH:7][cH:8]1)[Br:27]

Participants

Reactant 3

HCID 6344Dichloromethane

HCID 24614Phosphorus tribromide

HCID 670073171-[2-(4-Hydroxymethyl-phenyl)-ethyl]-4-phenethyl-1H-pyridin-2-one

Product 1

HCID 670066581-[2-(4-Bromomethyl-phenyl)-ethyl]-4-phenethyl-1H-pyridin-2-one

Sources & evidence

ORD record: ord-ed2ffbe75e2146cab141ba4ba80fea1a
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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