2-(Dimethyl-1,2-oxazol-4-yl)acetic acid → HCID 25255569, compound

Reaction equation

[CH3:29][c:30]1[n:31][o:32][c:33]([CH3:39])[c:34]1[CH2:35][C:36](=[O:37])[OH:38].[NH2:1][c:2]1[cH:3][c:4]([F:28])[c:5]([C:8]([CH2:9][N:10]2[C:11]([CH3:26])=[N:12][C:13]([CH2:16][CH2:17][CH3:18])([c:19]3[cH:20][cH:21][c:22]([F:25])[cH:23][cH:24]3)[C:14]2=[O:15])=[O:27])[cH:6][cH:7]1>>[NH:1]([c:2]1[cH:3][c:4]([F:28])[c:5]([C:8]([CH2:9][N:10]2[C:11]([CH3:26])=[N:12][C:13]([CH2:16][CH2:17][CH3:18])([c:19]3[cH:20][cH:21][c:22]([F:25])[cH:23][cH:24]3)[C:14]2=[O:15])=[O:27])[cH:6][cH:7]1)[C:36]([CH2:35][c:34]1[c:30]([CH3:29])[n:31][o:32][c:33]1[CH3:39])=[O:37]

Participants

Reactant 2

HCID 20633382-(Dimethyl-1,2-oxazol-4-yl)acetic acid

HCID 684625703-[2-(4-Amino-2-fluoro-phenyl)-2-oxo-ethyl]-5-(4-fluoro-phenyl)-2-methyl-5-propyl-3,5-dihydro-imidazol-4-one

Product 1

HCID 25255569HCID 25255569, compound

Sources & evidence

ORD record: ord-f70a83f1a9ac4ab287f59db30a848254
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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