2-Aminopyrimidine-5-boronic acid, pinacol ester → 5-(4-Morpholino-6-((4-(piperidin-1-yl)piperidin-1-yl)methyl)thieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine
Reaction equation
[CH3:30][C:31]1([CH3:32])[C:33]([CH3:34])([CH3:35])[O:36][B:37]([c:38]2[cH:39][n:40][c:41]([NH2:44])[n:42][cH:43]2)[O:45]1.[Cl:1][c:2]1[n:3][c:4]([N:24]2[CH2:25][CH2:26][O:27][CH2:28][CH2:29]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][N:12]1[CH2:13][CH2:14][CH:15]([N:18]3[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]3)[CH2:16][CH2:17]1)[s:10]2>>[c:2]1(-[c:38]2[cH:39][n:40][c:41]([NH2:44])[n:42][cH:43]2)[n:3][c:4]([N:24]2[CH2:25][CH2:26][O:27][CH2:28][CH2:29]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][N:12]1[CH2:13][CH2:14][CH:15]([N:18]3[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]3)[CH2:16][CH2:17]1)[s:10]2Participants
3
Sources & evidence
- ORD record
- ord-97f8e6c7f646468788f8ea13856da582
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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