Dimethyl Sulfoxide → (1H-Indol-5-yl)-(2-thiophen-2-yl-thieno[3,2-b]pyridin-7-yl)-amine

Reaction equation

[Br:9][c:10]1[cH:11][c:12]2[n:13][cH:14][cH:15][c:16]([NH:19][c:20]3[cH:21][c:22]4[cH:23][cH:24][nH:25][c:26]4[cH:27][cH:28]3)[c:17]2[s:18]1.[CH3:29][S:30]([CH3:31])=[O:32].[s:1]1[c:2]([B:6]([OH:7])[OH:8])[cH:3][cH:4][cH:5]1>>[s:1]1[c:2](-[c:10]2[cH:11][c:12]3[n:13][cH:14][cH:15][c:16]([NH:19][c:20]4[cH:21][c:22]5[cH:23][cH:24][nH:25][c:26]5[cH:27][cH:28]4)[c:17]3[s:18]2)[cH:3][cH:4][cH:5]1

Participants

Reactant 3

HCID 679Dimethyl Sulfoxide

HCID 27339602-Thiopheneboronic acid

HCID 18382766(2-bromo-thieno[3,2-b]pyridin-7-yl)-(1H-indol-5-yl)-amine

Product 1

HCID 9884654(1H-Indol-5-yl)-(2-thiophen-2-yl-thieno[3,2-b]pyridin-7-yl)-amine

Sources & evidence

ORD record: ord-6409f50fd7a448cd8a63ccf627affb06
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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