4-Bromobenzoyl chloride → 2-(4-Bromo-phenyl)-5-chloro-oxazolo[5,4-d]pyrimidine

HRID 81364

Reaction equation

HRID 81364 reaction equation
[Cl:1][C:2]1[N:3]=[CH:4][C:5]2[N:10]=[C:9]([C:11]3[CH:16]=[C:15](C)[C:14](OC)=[C:13](C)[CH:12]=3)[O:8][C:6]=2[N:7]=1.[Br:21]C1C=CC(C(Cl)=O)=CC=1>>[Br:21][C:14]1[CH:15]=[CH:16][C:11]([C:9]2[O:8][C:6]3[N:7]=[C:2]([Cl:1])[N:3]=[CH:4][C:5]=3[N:10]=2)=[CH:12][CH:13]=1

Participants

3

Reactant 2

HCID 685154-Bromobenzoyl chlorideHCID 866759545-Chloro-2-(4-methoxy-3,5-dimethylphenyl)oxazolo[5,4-d]pyrimidine

Product 1

HCID 866790702-(4-Bromo-phenyl)-5-chloro-oxazolo[5,4-d]pyrimidine

Procedure

The title compound was prepared analogously as described in example 1, steps (a) and (b), using 4-bromo benzoyl chloride in step (a).

Sources & evidence

ORD record
ord-35ac018577ae49678020d92aa86d090c
Source dataset
uspto-grants-2014_09
Patent number
US08846690B2

Linked notes

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