6-Bromonicotinic acid → (6-Bromopyridin-3-yl)[4-(2,4,5-trimethylphenyl)piperazin-1-yl]methanone
Reaction equation
[Br:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:7])[OH:8])[cH:9][cH:10]1.[CH3:11][c:12]1[c:13]([N:20]2[CH2:21][CH2:22][NH:23][CH2:24][CH2:25]2)[cH:14][c:15]([CH3:19])[c:16]([CH3:18])[cH:17]1>>[Br:1][c:2]1[n:3][cH:4][c:5]([C:6](=[O:8])[N:23]2[CH2:22][CH2:21][N:20]([c:13]3[c:12]([CH3:11])[cH:17][c:16]([CH3:18])[c:15]([CH3:19])[cH:14]3)[CH2:25][CH2:24]2)[cH:9][cH:10]1Participants
3
Sources & evidence
- ORD record
- ord-363de4fc422b46808b434f3254a59fa4
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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