Acetone → [1-(4-Methoxy-2,6-dimethyl-phenylsulfonyl)-piperidin-2-yl]-methanol

HRID 815130Notes

Reaction equation

HRID 815130 reaction equation
[CH3:29][C:30](=[O:31])[CH3:32].[CH3:7][O:8][c:9]1[cH:10][c:11]([CH3:20])[c:12]([S:16](=[O:17])(=[O:18])[Cl:19])[c:13]([CH3:15])[cH:14]1.[K+:1].[K+:2].[NH:21]1[CH:22]([CH2:27][OH:28])[CH2:23][CH2:24][CH2:25][CH2:26]1.[O-:3][C:4]([O-:5])=[O:6]>>[CH3:7][O:8][c:9]1[cH:10][c:11]([CH3:20])[c:12]([S:16](=[O:17])(=[O:18])[N:21]2[CH:22]([CH2:27][OH:28])[CH2:23][CH2:24][CH2:25][CH2:26]2)[c:13]([CH3:15])[cH:14]1

Participants

6

Reactant 5

HCID 180AcetoneHCID 813Potassium Cation2×HCID 19660Carbonate IonHCID 94263Piperidin-2-ylmethanolHCID 159174964-Methoxy-2,6-dimethylbenzene-1-sulfonyl chloride

Product 1

HCID 43574491[1-(4-Methoxy-2,6-dimethyl-phenylsulfonyl)-piperidin-2-yl]-methanol

Sources & evidence

ORD record
ord-43f3ca8ffb8648c79efa425fa090684e
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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