Pyridine → (RS)-1-Ethyl-7-fluoro-4-oxo-8-[3-(4-fluorophenyl)-1-piperazinyl]-1,4-dihydrobenzo[b][1,8]naphthyridine-3-carboxylic acid
Reaction equation
[Cl:1][c:2]1[c:3]([F:22])[cH:4][c:5]2[c:6]([n:7][c:8]3[n:9]([CH2:19][CH3:20])[cH:10][c:11]([C:16](=[O:17])[OH:18])[c:12](=[O:15])[c:13]3[cH:14]2)[cH:21]1.[F:23][c:24]1[cH:25][cH:26][c:27]([CH:30]2[NH:31][CH2:32][CH2:33][NH:34][CH2:35]2)[cH:28][cH:29]1.[cH:36]1[cH:37][cH:38][n:39][cH:40][cH:41]1>>[c:2]1([N:34]2[CH2:33][CH2:32][NH:31][CH:30]([c:27]3[cH:26][cH:25][c:24]([F:23])[cH:29][cH:28]3)[CH2:35]2)[c:3]([F:22])[cH:4][c:5]2[c:6]([n:7][c:8]3[n:9]([CH2:19][CH3:20])[cH:10][c:11]([C:16](=[O:17])[OH:18])[c:12](=[O:15])[c:13]3[cH:14]2)[cH:21]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-7b5cbe4140554a999a7bd4b2a509dc9b
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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