tert-Butyl acrylate → tert-butyl 3-(1'-methyl-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl)prop-2-enoate

HRID 816998

Reaction equation

HRID 816998 reaction equation
[C:48]([CH3:49])([CH3:50])([CH3:51])[O:52][C:53]([CH:54]=[CH2:55])=[O:56].[CH3:19][O:20][C:21](=[O:22])[CH:23]=[CH:24][c:25]1[cH:26][c:27]2[c:28]([cH:29][cH:30]1)[O:31][C:32]1([CH2:33][CH2:34][N:35]([C:36]([O:37][C:38]([CH3:39])([CH3:40])[CH3:41])=[O:42])[CH2:43][CH2:44]1)[CH2:45][C:46]2=[O:47].[CH3:1][N:2]1[CH2:3][CH2:4][C:5]2([O:6][c:7]3[cH:8][cH:9][c:10]([Br:16])[cH:11][c:12]3[C:13](=[O:15])[CH2:14]2)[CH2:17][CH2:18]1>>[CH3:1][N:2]1[CH2:3][CH2:4][C:5]2([O:6][c:7]3[cH:8][cH:9][c:10]([CH:55]=[CH:54][C:53]([O:52][C:48]([CH3:49])([CH3:50])[CH3:51])=[O:56])[cH:11][c:12]3[C:13](=[O:15])[CH2:14]2)[CH2:17][CH2:18]1

Participants

4

Reactant 3

HCID 15458tert-Butyl acrylateHCID 577208056-Bromo-1'-methylspiro[chroman-2,4'-piperidin]-4-oneHCID 66932397tert-butyl 6-(3-methoxy-3-oxoprop-1-enyl)-4-oxospiro[3H-chromene-2,4'-piperidine]-1'-carboxylate

Product 1

HCID 66932299tert-butyl 3-(1'-methyl-4-oxospiro[3H-chromene-2,4'-piperidine]-6-yl)prop-2-enoate

Sources & evidence

ORD record
ord-9f64c0741a3846b6ac7f7294e750855c
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

Loading…