ethyl 6-chloro-8-iodo-2-(trifluoromethyl)-2H-chromene-3-carboxylate → ethyl 8-{[4-(aminosulfonyl)phenyl]ethynyl}-6-chloro-2-(trifluoromethyl)-2H-chromene-3-carboxylate
Reaction equation
[C:22](#[CH:23])[c:24]1[cH:25][cH:26][c:27]([S:30](=[O:31])(=[O:32])[NH2:33])[cH:28][cH:29]1.[Cl:1][c:2]1[cH:3][c:4]2[c:9]([c:10]([I:12])[cH:11]1)[O:8][CH:7]([C:13]([F:14])([F:15])[F:16])[C:6]([C:17](=[O:18])[O:19][CH2:20][CH3:21])=[CH:5]2>>[Cl:1][c:2]1[cH:3][c:4]2[c:9]([c:10]([C:23]#[C:22][c:24]3[cH:25][cH:26][c:27]([S:30](=[O:31])(=[O:32])[NH2:33])[cH:28][cH:29]3)[cH:11]1)[O:8][CH:7]([C:13]([F:14])([F:15])[F:16])[C:6]([C:17](=[O:18])[O:19][CH2:20][CH3:21])=[CH:5]2Participants
3
Sources & evidence
- ORD record
- ord-47169f2dc4db4aa0b6978f092a0851ca
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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