Dimethyl Sulfoxide → N,N-dibenzyl-8-(2-methylpyrimidin-5-yl)-1,2,3,4-tetrahydronaphthalen-2-amine

HRID 817993

Reaction equation

HRID 817993 reaction equation
[CH2:11]([c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1)[N:18]([CH:19]1[CH2:20][c:21]2[c:22]([Br:29])[cH:23][cH:24][cH:25][c:26]2[CH2:27][CH2:28]1)[CH2:30][c:31]1[cH:32][cH:33][cH:34][cH:35][cH:36]1.[CH3:1][c:2]1[n:3][cH:4][c:5]([B:8]([OH:9])[OH:10])[cH:6][n:7]1.[CH3:37][S:38]([CH3:39])=[O:40]>>[CH3:1][c:2]1[n:3][cH:4][c:5](-[c:22]2[c:21]3[c:26]([cH:25][cH:24][cH:23]2)[CH2:27][CH2:28][CH:19]([N:18]([CH2:11][c:12]2[cH:13][cH:14][cH:15][cH:16][cH:17]2)[CH2:30][c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[CH2:20]3)[cH:6][n:7]1

Participants

4

Reactant 3

HCID 679Dimethyl SulfoxideHCID 18622522N,N-dibenzyl-8-bromo-1,2,3,4-tetrahydronaphthalen-2-amineHCID 457872742-Methylpyrimidine-5-boronic acid

Product 1

HCID 140551735N,N-dibenzyl-8-(2-methylpyrimidin-5-yl)-1,2,3,4-tetrahydronaphthalen-2-amine

Sources & evidence

ORD record
ord-2880f1053603474cad91e1fa160b9c11
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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