Methanol → (2-Chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-[1-(2-methoxy-ethyl)-piperidin-4-yl]-methyl-amine

HRID 820505

Reaction equation

HRID 820505 reaction equation
[CH3:20][O:21][CH2:22][CH2:23][N:24]1[CH2:25][CH2:26][C:27](=[O:30])[CH2:28][CH2:29]1.[CH3:31][CH2:32][O:33][CH2:34][CH3:35].[CH3:36][OH:37].[Cl:1][c:2]1[n:3][c:4]([N:14]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][NH:12][CH3:13])[s:10]2>>[Cl:1][c:2]1[n:3][c:4]([N:14]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][N:12]([CH3:13])[CH:27]1[CH2:26][CH2:25][N:24]([CH2:23][CH2:22][O:21][CH3:20])[CH2:29][CH2:28]1)[s:10]2

Participants

5

Reactant 4

HCID 887MethanolHCID 3283Diethyl EtherHCID 247102641-(2-Methoxyethyl)piperidin-4-oneHCID 595929371-(2-Chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)-N-methylmethanamine

Product 1

HCID 86619259(2-Chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-[1-(2-methoxy-ethyl)-piperidin-4-yl]-methyl-amine

Sources & evidence

ORD record
ord-538432e15d7d4a3d8c45cc3104344a3e
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

Loading…