1,4-Dioxane → 3-(5-fluoro-1H-indol-3-yl)piperidine-1-carboxylic acid-(4-dimethylamino-4-phenylcyclohexyl)-amide
Reaction equation
[F:26][c:27]1[cH:28][c:29]2[c:30]([CH:36]3[CH2:37][NH:38][CH2:39][CH2:40][CH2:41]3)[cH:31][nH:32][c:33]2[cH:34][cH:35]1.[O:42]1[CH2:43][CH2:44][O:45][CH2:46][CH2:47]1.[c:1]1([O:2][C:8]([NH:9][CH:10]2[CH2:11][CH2:12][C:13]([c:16]3[cH:17][cH:18][cH:19][cH:20][cH:21]3)([N:22]([CH3:23])[CH3:24])[CH2:14][CH2:15]2)=[O:25])[cH:3][cH:4][cH:5][cH:6][cH:7]1>>[C:8]([NH:9][CH:10]1[CH2:11][CH2:12][C:13]([c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)([N:22]([CH3:23])[CH3:24])[CH2:14][CH2:15]1)(=[O:25])[N:38]1[CH2:37][CH:36]([c:30]2[c:29]3[cH:28][c:27]([F:26])[cH:35][cH:34][c:33]3[nH:32][cH:31]2)[CH2:41][CH2:40][CH2:39]1Participants
4
Sources & evidence
- ORD record
- ord-3b3ffb52c8d54b8598048a63c08c2bd6
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
- DOI