Methanol → 3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-N-(2-hydroxy-ethoxy)-5-[(2-hydroxy-ethylamino)-methyl]-benzamide

Reaction equation

[BH4-:1].[CH3:32][OH:33].[F:3][c:4]1[c:5]([NH:23][c:24]2[c:25]([F:31])[cH:26][c:27]([I:30])[cH:28][cH:29]2)[c:6]([C:7](=[O:8])[NH:9][O:10][CH2:11][CH2:12][OH:13])[cH:14][c:15]([CH:18]=[N:19][CH2:20][CH2:21][OH:22])[c:16]1[F:17].[Na+:2]>>[F:3][c:4]1[c:5]([NH:23][c:24]2[c:25]([F:31])[cH:26][c:27]([I:30])[cH:28][cH:29]2)[c:6]([C:7](=[O:8])[NH:9][O:10][CH2:11][CH2:12][OH:13])[cH:14][c:15]([CH2:18][NH:19][CH2:20][CH2:21][OH:22])[c:16]1[F:17]