HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Phenylpropionic acid, (-)- → (2R)-N-{5-[(7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)carbonyl]pyridin-3-yl}-2-phenylpropanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Phenylpropionic acid, (-)- | HCID 446626 | — |
| Reactant | (5-aminopyridin-3-yl)(7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)methanone | HCID 70817432 | — |
| Product | (2R)-N-{5-[(7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)carbonyl]pyridin-3-yl}-2-phenylpropanamide | HCID 70817805 | — |
Reaction Steps
The title compound was prepared according to the method described for Library protocol 1 starting from (5-amino-pyridin-3-yl)-(7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-methanone (Preparation 110) and (2R)-2-phenylpropanoic acid to afford the title compound. LCMS: Rt=2.52 min; m/z 386 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08846698B2 |
| Source dataset | uspto-grants-2014_09 |
| ORD ID | ord-ca43962c1c6741d6b3b4d46803ec2686 |
| Source note | uspto-grants-2014_09 |