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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 82178Generated: October 25, 2026

3-Oxetanamine → 4-Chloro-7-oxetan-3-yl-7H-pyrrolo[2,3-d]pyrimidine

https://huagongshe.com/reaction/82178

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-OxetanamineHCID 9833923—
Reactant(4,6-Dichloropyrimidin-5-yl)acetaldehydeHCID 13989292—
Product4-Chloro-7-oxetan-3-yl-7H-pyrrolo[2,3-d]pyrimidineHCID 86672098—

Reaction Steps

The title compound was prepared according to the method described for Preparation 1 using (4,6-dichloropyrimidin-5-yl)acetaldehyde (Preparation 208) and oxetan-3-amine to afford the title compound as a yellow solid in 67% yield, 2.81 g.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846698B2
Source datasetuspto-grants-2014_09
ORD IDord-da372c854fd145ceb2cc65ad5ec2537d
Source noteuspto-grants-2014_09