7-fluoro-1H-indazol-3-amine → [2-(2-Chloro-phenyl)-pyrido[2,3-d]pyrimidin-4-yl]-(7-fluoro-1H-indazol-3-yl)-amine

Reaction equation

[Cl:1][c:2]1[c:3]2[c:4]([n:5][c:6](-[c:8]3[c:9]([Cl:14])[cH:10][cH:11][cH:12][cH:13]3)[n:7]1)[n:15][cH:16][cH:17][cH:18]2.[F:19][c:20]1[cH:21][cH:22][cH:23][c:24]2[c:25]([NH2:29])[n:26][nH:27][c:28]12>>[c:2]1([NH:29][c:25]2[c:24]3[cH:23][cH:22][cH:21][c:20]([F:19])[c:28]3[nH:27][n:26]2)[c:3]2[c:4]([n:5][c:6](-[c:8]3[c:9]([Cl:14])[cH:10][cH:11][cH:12][cH:13]3)[n:7]1)[n:15][cH:16][cH:17][cH:18]2

Participants

Reactant 2

HCID 8179087-fluoro-1H-indazol-3-amine

HCID 219392444-Chloro-2-(2-chloro-phenyl)-pyrido(2,3-d]pyrimidine

Product 1

HCID 21939265[2-(2-Chloro-phenyl)-pyrido[2,3-d]pyrimidin-4-yl]-(7-fluoro-1H-indazol-3-yl)-amine

Sources & evidence

ORD record: ord-85fc2fdf481a445d9746d470c10e2235
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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