Ethanol → 1-(1-(5-Pyrimidinyl)-ethyl)-4-oxopiperidine

HRID 824505Notes

Reaction equation

HRID 824505 reaction equation
[CH3:10][CH2:11][OH:12].[CH3:20][N+:21]1([CH3:28])[CH2:22][CH2:23][C:24](=[O:27])[CH2:25][CH2:26]1.[I-:19].[K+:13].[K+:14].[NH2:1][CH:2]([CH3:3])[c:4]1[cH:5][n:6][cH:7][n:8][cH:9]1.[O-:15][C:16]([O-:17])=[O:18].[OH2:29]>>[N:1]1([CH:2]([CH3:3])[c:4]2[cH:5][n:6][cH:7][n:8][cH:9]2)[CH2:22][CH2:23][C:24](=[O:27])[CH2:25][CH2:26]1

Participants

8

Reactant 7

HCID 702EthanolHCID 813Potassium Cation2×HCID 962WaterHCID 19660Carbonate IonHCID 30165Iodide IonHCID 4229661,1-Dimethyl-4-oxopiperidinium iodideHCID 189142881-(Pyrimidin-5-yl)ethanamine

Product 1

HCID 189142901-(1-(5-Pyrimidinyl)-ethyl)-4-oxopiperidine

Sources & evidence

ORD record
ord-8714c922baba4fc9b623dfeef0c9c2a4
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Reaction notes

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