Carbon Disulfide → HCID 178527819, compound
Reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([NH2:7])[C:2]=1[NH2:8].[C:9](=S)=[S:10]>CCO>[NH:7]1[C:3]2[C:2](=[N:1][CH:6]=[CH:5][CH:4]=2)[N:8]=[C:9]1[SH:10]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Conditions
- Temperature
- 40 °C
Procedure
To a solution of pyridine-2,3-diamine (5 g) in EtOH (150 ml) was added carbon disulfide (23 mL) at room temperature. The mixture was stirred at 40° C. under Ar for 10 h. The mixture was cooled to room temperature. The resulting white solid was filtered and washed with ether to give 1H-imidazo[4,5-b]pyridine-2-thiol (5.61 g).
Workup
- temperatureThe mixture was cooled to room temperature
- filtrationThe resulting white solid was filtered
- washwashed with ether
Sources & evidence
- ORD record
- ord-ea7d4add4185470b924efe62d498fe9b
- Source dataset
- uspto-grants-2014_09
- Patent number
- US08846713B2
Reaction notes
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