Acetyl chloride → 1-(2-Chloro-7-cyclopentyl-6-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-ethanone

Reaction equation

[CH3:17][C:18]([Cl:19])=[O:20].[Cl:1][c:2]1[n:3][cH:4][c:5]2[c:6]([n:7]1)[n:8]([CH:12]1[CH2:13][CH2:14][CH2:15][CH2:16]1)[c:9]([CH3:11])[cH:10]2.[Cl:21][c:22]1[n:23][cH:24][c:25]2[c:26]([C:27](=[O:28])[CH3:29])[cH:30][n:31]([CH:32]3[CH2:33][CH2:34][CH2:35][CH2:36]3)[c:37]2[n:38]1>>[Cl:1][c:2]1[n:3][cH:4][c:5]2[c:6]([n:7]1)[n:8]([CH:12]1[CH2:13][CH2:14][CH2:15][CH2:16]1)[c:9]([CH3:11])[c:10]2[C:18]([CH3:17])=[O:20]

Participants

Reactant 3

HCID 6367Acetyl chloride

HCID 848197792-Chloro-7-cyclopentyl-6-methyl-7H-pyrrolo[2,3-d]pyrimidine

HCID 866373431-(2-Chloro-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-ethanone

Product 1

HCID 866373441-(2-Chloro-7-cyclopentyl-6-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-ethanone

Sources & evidence

ORD record: ord-09f9871b03a5456fb25da17fae732bcd
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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