Acetic acid, 2-[4-(bromomethyl)phenoxy]-, methyl ester → (4-{3-[1-(3-Chloro-benzyl)-5,6-difluoro-1H-benzoimidazol-2-yl]-pyridin-2-yloxymethyl}-phenoxy)-acetic acid methyl ester
Reaction equation
[CH3:27][O:28][C:29]([CH2:30][O:31][c:32]1[cH:33][cH:34][c:35]([CH2:38][Br:39])[cH:36][cH:37]1)=[O:40].[Cl:1][c:2]1[cH:3][c:4]([CH2:5][n:6]2[c:7](-[c:17]3[c:18]([OH:23])[n:19][cH:20][cH:21][cH:22]3)[n:8][c:9]3[c:10]2[cH:11][c:12]([F:16])[c:13]([F:15])[cH:14]3)[cH:24][cH:25][cH:26]1>>[Cl:1][c:2]1[cH:3][c:4]([CH2:5][n:6]2[c:7](-[c:17]3[c:18]([O:23][CH2:38][c:35]4[cH:34][cH:33][c:32]([O:31][CH2:30][C:29]([O:28][CH3:27])=[O:40])[cH:37][cH:36]4)[n:19][cH:20][cH:21][cH:22]3)[n:8][c:9]3[c:10]2[cH:11][c:12]([F:16])[c:13]([F:15])[cH:14]3)[cH:24][cH:25][cH:26]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-9275028575be48039b9d211be12f531d
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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