4-(3,4-Difluorophenoxy)benzaldehyde → N-(3-{1-[4-(3,4-Difluorophenoxy)benzyl]-4-piperidinyl}-4-methylphenyl)-2-methylpropanamide
Reaction equation
[CH3:18][CH:19]([C:20](=[O:21])[NH:22][c:23]1[cH:24][c:25]([CH:30]2[CH2:31][CH2:32][NH:33][CH2:34][CH2:35]2)[c:26]([CH3:29])[cH:27][cH:28]1)[CH3:36].[F:1][c:2]1[cH:3][c:4]([O:5][c:6]2[cH:7][cH:8][c:9]([CH:10]=[O:11])[cH:12][cH:13]2)[cH:14][cH:15][c:16]1[F:17]>>[F:1][c:2]1[cH:3][c:4]([O:5][c:6]2[cH:7][cH:8][c:9]([CH2:10][N:33]3[CH2:32][CH2:31][CH:30]([c:25]4[cH:24][c:23]([NH:22][C:20]([CH:19]([CH3:18])[CH3:36])=[O:21])[cH:28][cH:27][c:26]4[CH3:29])[CH2:35][CH2:34]3)[cH:12][cH:13]2)[cH:14][cH:15][c:16]1[F:17]Participants
3
Sources & evidence
- ORD record
- ord-38a285a06fc448cab94ed9d755df54ed
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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