1-(2-Furoyl)piperazine → 6-Fluoro-2-oxo-4-[4-(furan-2-carbonyl)-piperazine-1-yl]-1,2-dihydro-[1,8]-naphthyridine-3-carbonitrile
Reaction equation
[Cl:1][c:2]1[c:3]([C:14]#[N:15])[c:4](=[O:13])[nH:5][c:6]2[n:7][cH:8][c:9]([F:12])[cH:10][c:11]12.[o:16]1[c:17]([C:21](=[O:22])[N:23]2[CH2:24][CH2:25][NH:26][CH2:27][CH2:28]2)[cH:18][cH:19][cH:20]1>>[c:2]1([N:26]2[CH2:25][CH2:24][N:23]([C:21]([c:17]3[o:16][cH:20][cH:19][cH:18]3)=[O:22])[CH2:28][CH2:27]2)[c:3]([C:14]#[N:15])[c:4](=[O:13])[nH:5][c:6]2[n:7][cH:8][c:9]([F:12])[cH:10][c:11]12Participants
3
Sources & evidence
- ORD record
- ord-9f82d4068a2f41748bf0a49b441dab86
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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