tert-Butyl {1-[2-(6-methoxy-3-oxo-2,3-dihydro-4H-1,4-benzoxazin-4-yl)ethyl]piperidine-4-yl}carbamate → 4-[2-(4-Aminopiperidin-1-yl)ethyl]-6-methoxy-2H-1,4-benzoxazin 3 (4H)-one
Reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:7]([cH:29]1)[N:8]([CH2:13][CH2:14][N:15]1[CH2:16][CH2:17][CH:18]([NH:21][C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[CH2:19][CH2:20]1)[C:9](=[O:12])[CH2:10][O:11]2.[NH2:30][CH:31]1[CH2:32][CH2:33][N:34]([CH2:35][CH2:36][n:37]2[c:38]3[c:39]([cH:40][cH:41][c:42]([C:43]#[N:44])[cH:45]3)[cH:46][cH:47][c:48]2=[O:49])[CH2:50][CH2:51]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:7]([cH:29]1)[N:8]([CH2:13][CH2:14][N:15]1[CH2:16][CH2:17][CH:18]([NH2:21])[CH2:19][CH2:20]1)[C:9](=[O:12])[CH2:10][O:11]2Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-5d6e3a768116427db13fa23a0f377c45
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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