Chloroacetonitrile → [2-Fluoro-5-(7-trifluoromethyl[1,8]naphthyridin-4-yl)phenoxy]acetonitrile
Reaction equation
[Cl:23][CH2:24][C:25]#[N:26].[F:1][c:2]1[c:3]([OH:22])[cH:4][c:5](-[c:8]2[cH:9][cH:10][n:11][c:12]3[n:13][c:14]([C:18]([F:19])([F:20])[F:21])[cH:15][cH:16][c:17]23)[cH:6][cH:7]1>>[F:1][c:2]1[c:3]([O:22][CH2:24][C:25]#[N:26])[cH:4][c:5](-[c:8]2[cH:9][cH:10][n:11][c:12]3[n:13][c:14]([C:18]([F:19])([F:20])[F:21])[cH:15][cH:16][c:17]23)[cH:6][cH:7]1Participants
3
Sources & evidence
- ORD record
- ord-40c6acb73b4444099fb955942d9dfec3
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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