2,5-Bis(trifluoromethyl)benzaldehyde → 6-[4-(2,5-Bis-trifluoromethyl-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one
Reaction equation
[F:14][C:15]([c:16]1[c:17]([CH:18]=[O:19])[cH:20][c:21]([C:24]([F:25])([F:26])[F:27])[cH:22][cH:23]1)([F:28])[F:29].[N:1]1([c:7]2[cH:8][c:9](=[O:13])[nH:10][cH:11][n:12]2)[CH2:2][CH2:3][NH:4][CH2:5][CH2:6]1>>[N:1]1([c:7]2[cH:8][c:9](=[O:13])[nH:10][cH:11][n:12]2)[CH2:2][CH2:3][N:4]([CH2:18][c:17]2[c:16]([C:15]([F:14])([F:28])[F:29])[cH:23][cH:22][c:21]([C:24]([F:25])([F:26])[F:27])[cH:20]2)[CH2:5][CH2:6]1Participants
3
Sources & evidence
- ORD record
- ord-8635996ac79a4d72a53f136851239f27
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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