HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Hydroxide → 6-Amino-4-(2-furyl)-1H-pyrazolo[3,4-d]pyrimidin-1-ylacetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | ethyl 6-amino-4-(2-furyl)-1H-pyrazolo[3,4-d]pyrimidin-1-ylacetate | HCID 22015527 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 6-Amino-4-(2-furyl)-1H-pyrazolo[3,4-d]pyrimidin-1-ylacetic acid | HCID 22015531 | 95% |
Reaction Steps
A solution of ethyl 6-amino-4-(2-furyl)-1H-pyrazolo[3,4-d]pyrimidin-1-ylacetate (350 mg, 1.22 mmol) in MeOH (2 mL) was treated with NaOH (1-M, 1 mL, 1 mmol), refluxed for 15 min, cooled, acidified and filtered to give the title compound (300 mg, 95%) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07087754B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-5e488aaa93084100a887369eb5c0f859 |
| Source note | uspto-grants-2006_08 |