Potassium Cation → 1-(5-(2-(4-(2-(Azetidine-1-carbonyl)benzofuran-7-yl)piperazin-1-yl)ethyl)indolin-1-yl)ethanone

HRID 830017

Reaction equation

HRID 830017 reaction equation
[Br:22][CH2:23][CH2:24][c:25]1[cH:26][c:27]2[c:31]([cH:32][cH:33]1)[N:30]([C:34]([CH3:35])=[O:36])[CH2:29][CH2:28]2.[C:37](=[O:38])([O-:39])[O-:40].[CH3:43][C:44]#[N:45].[K+:41].[K+:42].[N:1]1([C:5](=[O:6])[c:7]2[o:8][c:9]3[c:10]([cH:11]2)[cH:12][cH:13][cH:14][c:15]3[N:16]2[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]2)[CH2:2][CH2:3][CH2:4]1>>[N:1]1([C:5](=[O:6])[c:7]2[o:8][c:9]3[c:10]([cH:11]2)[cH:12][cH:13][cH:14][c:15]3[N:16]2[CH2:17][CH2:18][N:19]([CH2:23][CH2:24][c:25]3[cH:26][c:27]4[c:31]([cH:32][cH:33]3)[N:30]([C:34]([CH3:35])=[O:36])[CH2:29][CH2:28]4)[CH2:20][CH2:21]2)[CH2:2][CH2:3][CH2:4]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6342AcetonitrileHCID 19660Carbonate IonHCID 517132361-(5-(2-Bromoethyl)indolin-1-yl)ethanoneHCID 59636763Azetidin-1-yl(7-(piperazin-1-yl)benzofuran-2-yl)methanone

Product 1

HCID 596367211-(5-(2-(4-(2-(Azetidine-1-carbonyl)benzofuran-7-yl)piperazin-1-yl)ethyl)indolin-1-yl)ethanone

Sources & evidence

ORD record
ord-34ad2067947246d5b8059866cc0eeef8
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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