5-Hexyn-1-ol → 6-[2-Amino-4-chloro-7-(4-methoxy-3,5-dimethyl-pyridin-2-ylmethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-hex-5-yn-1-ol
Reaction equation
[CH2:24]([CH2:25][CH2:26][CH2:27][C:28]#[CH:29])[OH:30].[Cl:1][c:2]1[c:3]2[c:4]([n:5][c:6]([NH2:8])[n:7]1)[n:9]([CH2:13][c:14]1[n:15][cH:16][c:17]([CH3:23])[c:18]([O:21][CH3:22])[c:19]1[CH3:20])[cH:10][c:11]2[I:12]>>[Cl:1][c:2]1[c:3]2[c:4]([n:5][c:6]([NH2:8])[n:7]1)[n:9]([CH2:13][c:14]1[n:15][cH:16][c:17]([CH3:23])[c:18]([O:21][CH3:22])[c:19]1[CH3:20])[cH:10][c:11]2[C:29]#[C:28][CH2:27][CH2:26][CH2:25][CH2:24][OH:30]Participants
3
Sources & evidence
- ORD record
- ord-42a0f2e2f7f24f2db335e4bdf651c2bb
- Source dataset
- Test data from https://doi.org/10.1039/C8SC04228D
Reaction notes
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