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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 8304Generated: October 26, 2026

Bromine → 4-Bromo-2,6-difluoropyridine

https://huagongshe.com/reaction/8304

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBromineHCID 24408—
Reactant2,6-Difluoropyridine-4-boronic acidHCID 2762747—
Reactant2,6-Difluoro-4-hydrazinylpyridineHCID 12175810—
Product4-Bromo-2,6-difluoropyridineHCID 22015559—

Reaction Steps

The second step in the synthetic procedure used in synthesizing the 2,6-difluoropyridin-4-ylboronic acid involves bromination of 2,6-difluoro-4-hydrazinopyridine by elemental bromine to produce 4-bromo-2,6-difluoropyridine. This reaction can be depicted as follows:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07087755B1
Source datasetuspto-grants-2006_08
ORD IDord-b56817fc57374cc58bfa3e46d9d16bc2
Source noteuspto-grants-2006_08