Ethanol → [3-(4-Chloro-pyridin-2-yl)-thiophen-2-yl]-methanol

Reaction equation

[BH4-:15].[CH3:18][CH2:19][OH:20].[Cl:1][c:2]1[cH:3][c:4](-[c:8]2[c:9]([CH:13]=[O:14])[s:10][cH:11][cH:12]2)[n:5][cH:6][cH:7]1.[Na+:16].[OH2:17]>>[Cl:1][c:2]1[cH:3][c:4](-[c:8]2[c:9]([CH2:13][OH:14])[s:10][cH:11][cH:12]2)[n:5][cH:6][cH:7]1

Participants

Reactant 5

HCID 702Ethanol

HCID 923Sodium Ion

HCID 962Water

HCID 28123Borohydride

HCID 866286363-(4-Chloro-pyridin-2-yl)-thiophene-2-carbaldehyde

Product 1

HCID 67387562[3-(4-Chloro-pyridin-2-yl)-thiophen-2-yl]-methanol

Sources & evidence

ORD record: ord-8ef44676ac704053a7f81f56e866428d
Source dataset: Test data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

Reaction notes

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