(4-(Pyrrolidine-1-carbonyl)phenyl)boronic acid → [4-[4-[5-Methyl-4-[2-(2-methylpyrrolidin-1-yl)ethyl]-1,3-oxazol-2-yl]phenyl]phenyl]-pyrrolidin-1-ylmethanone

HRID 830919

Reaction equation

HRID 830919 reaction equation
[Br:17][c:18]1[cH:19][cH:20][c:21](-[c:24]2[o:25][c:26]([CH3:37])[c:27]([CH2:29][CH2:30][N:31]3[CH:32]([CH3:36])[CH2:33][CH2:34][CH2:35]3)[n:28]2)[cH:22][cH:23]1.[N:1]1([C:6](=[O:7])[c:8]2[cH:9][cH:10][c:11]([B:14]([OH:15])[OH:16])[cH:12][cH:13]2)[CH2:2][CH2:3][CH2:4][CH2:5]1>>[N:1]1([C:6](=[O:7])[c:8]2[cH:9][cH:10][c:11](-[c:18]3[cH:19][cH:20][c:21](-[c:24]4[o:25][c:26]([CH3:37])[c:27]([CH2:29][CH2:30][N:31]5[CH:32]([CH3:36])[CH2:33][CH2:34][CH2:35]5)[n:28]4)[cH:22][cH:23]3)[cH:12][cH:13]2)[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

3

Reactant 2

HCID 2773571(4-(Pyrrolidine-1-carbonyl)phenyl)boronic acidHCID 117100152-(4-Bromophenyl)-5-methyl-4-[2-(2-methylpyrrolidin-1-yl)ethyl]-1,3-oxazole

Product 1

HCID 68702104[4-[4-[5-Methyl-4-[2-(2-methylpyrrolidin-1-yl)ethyl]-1,3-oxazol-2-yl]phenyl]phenyl]-pyrrolidin-1-ylmethanone

Sources & evidence

ORD record
ord-7b07dbf321a94cd5b7855750ff59a22b
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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