Acetic Anhydride → N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]acetamide

HRID 831282

Reaction equation

HRID 831282 reaction equation
[CH2:25]([CH2:26][O:27][CH3:28])[O:29][CH3:30].[CH3:18][C:19](=[O:20])[O:21][C:22](=[O:23])[CH3:24].[NH2:1][c:2]1[c:3]([N:12]2[CH2:13][CH2:14][O:15][CH2:16][CH2:17]2)[cH:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1>>[NH:1]([c:2]1[c:3]([N:12]2[CH2:13][CH2:14][O:15][CH2:16][CH2:17]2)[cH:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1)[C:19]([CH3:18])=[O:20]

Participants

4

Reactant 3

HCID 7918Acetic AnhydrideHCID 80711,2-DimethoxyethaneHCID 136624N-(2-Amino-4-(trifluoromethyl)phenyl)morpholine

Product 1

HCID 891590N-[2-morpholin-4-yl-5-(trifluoromethyl)phenyl]acetamide

Sources & evidence

ORD record
ord-d2e9bb0cf5e24af7aaa689080802cd78
Source dataset
Test data from https://doi.org/10.1039/C8SC04228D

Linked notes

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