HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Mesitylenesulfonyl chloride → 1-(Mesitylsulfonyl)-4-(1-piperazinyl)-1H-indole Hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Mesitylenesulfonyl chloride | HCID 13046 | — |
| Reactant | tert-Butyl 4-(1H-indol-4-yl)piperazine-1-carboxylate | HCID 22015386 | — |
| Product | 1-(Mesitylsulfonyl)-4-(1-piperazinyl)-1H-indole Hydrochloride | HCID 10295599 | — |
Reaction Steps
The title compound was prepared from 4-(4-boc-piperazinyl)-indole and mesitylsulfonylchloride according to Method 3: 1H NMR (270 MHz, DMSO-d6) δ 9.10 (br, 1 H), 7.71 (d, J=5 Hz, 1 H), 7.40–7.20 (m, 3 H), 7.00–6.80 (m, 2 H), 6.51 (d, J=8 Hz, 1 H), 3.30–3.20 (m, 8 H), 2.41 (s, 6 H), 2.27 (s, 3 H); MS (ESI+) for m/z 384 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07087750B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-d34fb486e4584bdcb5636a56b735f851 |
| Source note | uspto-grants-2006_08 |