HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxyamine hydrochloride → 17beta-Acetoxy-2,3-dihydroxyimino-5alpha-androstane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | Acetic acid, sodium salt, monohydrate | HCID 23681166 | — |
| Reactant | 2-Hydroxyimino-17beta-hydroxy-5alpha-androstan-3-one | HCID 86752163 | — |
| Solvent | Water | HCID 962 | — |
| Product | 17beta-Acetoxy-2,3-dihydroxyimino-5alpha-androstane | HCID 136395990 | — |
Reaction Steps
A suspension of steroid 7, NH2OH.HCl and NaOAc/H2O was refluxed for 20 minutes. The reaction was cooled to room temperature and poured into H2O. The precipitate was collected by filtration. The resulting solid 8 was washed with H2O and air and dried; wt. 23.4 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05723455 |
| Source dataset | uspto-grants-1998_03 |
| ORD ID | ord-4fe7e7b0295444c08046dd75241f89c9 |
| Source note | uspto-grants-1998_03 |